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Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration

INTRODUCTION: Results from our laboratory have demonstrated that intracerebroventricular administration of sildenafil to conscious rats promoted a noticeable increase in both lumbar sympathetic activity and heart rate, with no change in the mean arterial pressure. The intracerebroventricular adminis...

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Detalles Bibliográficos
Autores principales:	Bombarda, Gabriela, Sabino, João Paulo J., da Silva, Carlos Alberto A., Fazan, Rubens, Salgado, Maria Cristina O., Salgado, Helio C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161220/ https://www.ncbi.nlm.nih.gov/pubmed/21915492 http://dx.doi.org/10.1590/S1807-59322011000800017

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