Cargando…

Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide–deficient rats

OBJECTIVE: The aim of the present study was to assess the effects of rosuvastatin on renal injury and inflammation in a model of nitric oxide deficiency. METHODS: Male Wistar rats were randomly divided into four groups (n = 10/group) and treated for 28 days with saline (CTRL); 30 mg/kg/day L-NAME (L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Girardi, José Marcos, Farias, Rogério Estevan, Ferreira, Ana Paula, Raposo, Nádia Rezende Barbosa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161228/ https://www.ncbi.nlm.nih.gov/pubmed/21915500 http://dx.doi.org/10.1590/S1807-59322011000800025

Ejemplares similares

Prevalence of endothelial nitric oxide synthase (ENOS) gene G894T polymorphism and its association with hypertension: a population-based study with Brazilian women
por: Neto, Abel Barbosa Lira, et al.
Publicado: (2019)

Association between individual cholesterol and proteinuria response and exposure to atorvastatin or rosuvastatin
por: Kroonen, Marjolein Y. A. M., et al.
Publicado: (2019)

Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model
por: Shin, Seung Kak, et al.
Publicado: (2017)

Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria
por: Garsen, Marjolein, et al.
Publicado: (2016)

Comparison of the effect of rosuvastatin versus rosuvastatin/ezetimibe on markers of inflammation in patients with acute myocardial infarction
por: Ren, Yizhi, et al.
Publicado: (2017)

Involvement of nitric oxide pathways in neurogenic pulmonary edema induced by vagotomy
por: Blanco, Eleonora, et al.
Publicado: (2011)

Characterisation and comparison of temporal release profiles of nitric oxide generating donors
por: Bradley, Sophie A., et al.
Publicado: (2015)

The role of nitric oxide on rosuvastatin-mediated S-nitrosylation and translational proteomes in human umbilical vein endothelial cells
por: Huang, Bin, et al.
Publicado: (2012)

ASSESSMENT OF SERUM HOMOCYSTEINE, ENDOTHELIN-1, AND NITRIC OXIDE LEVELS IN BEHÇET’S DISEASE
por: Hodeib, Abeer A, et al.
Publicado: (2010)

Inducible nitric oxide synthase increases secretion from inflamed salivary glands
por: Correia, Patricia N., et al.
Publicado: (2010)

Nitric Oxide Metabolite Concentration in Cerebrospinal Fluid: Useful as a Prognostic Marker?
por: Singh, Saurabh, et al.
Publicado: (2016)

Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells
por: Pandey, Arvind K., et al.
Publicado: (2022)

Calciprotein Particles Induce Endothelial Dysfunction by Impairing Endothelial Nitric Oxide Metabolism
por: Feenstra, Lian, et al.
Publicado: (2023)

Short-term effect of the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxide synthase activity
por: Ludolph, Barbara, et al.
Publicado: (2007)

Sodium Nitroprusside as a Nitric Oxide Donor in a Rat Intestinal Ischemia-Reperfusion Model
por: Emre, Ali, et al.
Publicado: (2008)

Diabetic Nephropathy: Proteinuria, Inflammation, and Fibrosis
por: Zheng, Shirong, et al.
Publicado: (2016)

Piper Sarmentosum Increases Nitric Oxide Production in Oxidative Stress: A Study on Human Umbilical Vein Endothelial Cells
por: Ugusman, Azizah, et al.
Publicado: (2010)

Rosuvastatin induced photolocalized purpura
por: Thabouti, Marwa, et al.
Publicado: (2022)

Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ
por: Yamaguchi, Junna, et al.
Publicado: (2015)

Nitric oxide contributes to learning and memory deficits observed in hypothyroid rats during neonatal and juvenile growth
por: Hosseini, Mahmoud, et al.
Publicado: (2010)

Soy Isoflavone Improved Female Sexual Dysfunction of Mice Via Endothelial Nitric Oxide Synthase Pathway
por: Zhang, Jing, et al.
Publicado: (2019)

Impact of endothelial nitric oxide synthase activation on accelerated liver regeneration in a rat ALPPS model
por: Masuo, Hitoshi, et al.
Publicado: (2023)

Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis
por: Zhang, Xinbo, et al.
Publicado: (2020)

Nitric Oxide Gene Polymorphism is a Risk Factor for Diabetic Nephropathy and Atherosclerosis in Type 1 Diabetic Patients
por: Dayem, Soha M. Abd El, et al.
Publicado: (2019)

Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering
por: Yu, Pei, et al.
Publicado: (2018)

EFFECTS OF PROTEINURIA ON THE KIDNEY : PROTEINURIA, RENAL ENLARGEMENT, AND RENAL INJURY CONSEQUENT ON PROTRACTED PARENTERAL ADMINISTRATION OF PROTEIN SOLUTIONS IN RATS
por: Baxter, James H., et al.
Publicado: (1949)

The protective effect of cilostazol on isolated rabbit femoral arteries under conditions of ischemia and reperfusion: the role of the nitric oxide pathway
por: Santos, Mariana R.G.A., et al.
Publicado: (2012)

Region-dependent effects of diabetes and insulin-replacement on neuronal nitric oxide synthase- and heme oxygenase-immunoreactive submucous neurons
por: Bódi, Nikolett, et al.
Publicado: (2017)

Rosuvastatin attenuates contrast-induced nephropathy through modulation of nitric oxide, inflammatory responses, oxidative stress and apoptosis in diabetic male rats
por: Deng, Jie, et al.
Publicado: (2015)

Chronic treatment with the nitric oxide synthase inhibitor, (L)-NAME, attenuates estradiol-mediated improvement of learning and memory in ovariectomized rats
por: Azizi-Malekabadi, Hamid, et al.
Publicado: (2011)

Rosuvastatin-Induced Acute Interstitial Nephritis
por: Londrino, Francesco, et al.
Publicado: (2013)

nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe(−/−) Mice
por: Lallemand, Tom, et al.
Publicado: (2018)

Diagnostic approach to orthostatic proteinuria: a combination of urine micro-proteinuria with ultrasonography of the left renal vein
por: Kovvuru, Karthik, et al.
Publicado: (2020)

Influence of rosuvastatin treatment on cerebral inflammation and nitro-oxidative stress in experimental lung injury in pigs
por: Kamuf, Jens, et al.
Publicado: (2021)

Analysis of the nitric oxide-cyclic guanosine monophosphate pathway in experimental liver cirrhosis suggests phosphodiesterase-5 as potential target to treat portal hypertension
por: Schaffner, Denise, et al.
Publicado: (2018)

Urinary cytokines after hematopoietic cell transplantation: Evidence for renal inflammation in the pathogenesis of proteinuria and kidney disease
por: Hingorani, Sangeeta
Publicado: (2013)

Current Perspectives on rosuvastatin
por: Hu, Miao, et al.
Publicado: (2013)

Terahertz spectra of proteinuria and non-proteinuria
por: Xue, Zhenrui, et al.
Publicado: (2023)

Resveratrol-nitric oxide donor hybrid effect on priapism in sickle cell and nitric oxide-deficient mouse
por: Pinheiro, Andressa Kely, et al.
Publicado: (2022)

Polydimethylsiloxane: a new contrast material for localization of occult breast lesions
por: Vitral, Geraldo Sérgio Farinazzo, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8gi3lpvgs1cklnh0gmeq6f8nei