Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet β-Cells

OBJECTIVE: Ghrelin reportedly restricts insulin release in islet β-cells via the Gα(i2) subtype of G-proteins and thereby regulates glucose homeostasis. This study explored whether ghrelin regulates cAMP signaling and whether this regulation induces insulinostatic cascade in islet β-cells. RESEARCH...

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Detalles Bibliográficos
Autores principales: Dezaki, Katsuya, Damdindorj, Boldbaatar, Sone, Hideyuki, Dyachok, Oleg, Tengholm, Anders, Gylfe, Erik, Kurashina, Tomoyuki, Yoshida, Masashi, Kakei, Masafumi, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161328/
https://www.ncbi.nlm.nih.gov/pubmed/21788571
http://dx.doi.org/10.2337/db11-0368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161328/
https://www.ncbi.nlm.nih.gov/pubmed/21788571
http://dx.doi.org/10.2337/db11-0368

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