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Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice

OBJECTIVE: The therapeutic potential of exendin-4, an agonist of the glucagon-like peptide-1 receptor (GLP-1R), on diabetic polyneuropathy (DPN) in streptozotocin (STZ)-induced diabetic mice was investigated. RESEARCH DESIGN AND METHODS: The presence of the GLP-1R in lumbar dorsal root ganglion (DRG...

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Detalles Bibliográficos
Autores principales: Himeno, Tatsuhito, Kamiya, Hideki, Naruse, Keiko, Harada, Norio, Ozaki, Nobuaki, Seino, Yusuke, Shibata, Taiga, Kondo, Masaki, Kato, Jiro, Okawa, Tetsuji, Fukami, Ayako, Hamada, Yoji, Inagaki, Nobuya, Seino, Yutaka, Drucker, Daniel J., Oiso, Yutaka, Nakamura, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161330/
https://www.ncbi.nlm.nih.gov/pubmed/21810596
http://dx.doi.org/10.2337/db10-1462