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Islet Amyloid Polypeptide Is a Target Antigen for Diabetogenic CD4(+) T Cells

OBJECTIVE: To investigate autoantigens in β-cells, we have used a panel of pathogenic T-cell clones that were derived from the NOD mouse. Our particular focus in this study was on the identification of the target antigen for the highly diabetogenic T-cell clone BDC-5.2.9. RESEARCH DESIGN AND METHODS...

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Detalles Bibliográficos
Autores principales:	Delong, Thomas, Baker, Rocky L., Reisdorph, Nichole, Reisdorph, Richard, Powell, Roger L., Armstrong, Michael, Barbour, Gene, Bradley, Brenda, Haskins, Kathryn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161333/ https://www.ncbi.nlm.nih.gov/pubmed/21734016 http://dx.doi.org/10.2337/db11-0288

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