Cargando…

A novel genetically-obese rat model with elevated 11beta-hydroxysteroid dehydrogenase type 1 activity in subcutaneous adipose tissue

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrome. 11β-HSD1 activity is lower in liver and higher in omental adipose tissue of obese rodent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prasad, Sakamuri SS Vara, Prashanth, Anamthathmakula, Kumar, Chodavarapu Pavan, Reddy, Sirisha J, Giridharan, Nappan V, Vajreswari, Ayyalasomayajula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Short Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161380/ https://www.ncbi.nlm.nih.gov/pubmed/21083914 http://dx.doi.org/10.1186/1476-511X-9-132

Ejemplares similares

Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats
por: Sakamuri, Vara Prasad SS, et al.
Publicado: (2011)

Dietary fatty acid composition alters 11β-hydroxysteroid dehydrogenase type 1 gene expression in rat retroperitoneal white adipose tissue
por: Vara Prasad, Sakamuri SS, et al.
Publicado: (2010)

Transcriptome profiling of visceral adipose tissue in a novel obese rat model, WNIN/Ob & its comparison with other animal models
por: Sakamuri, Siva Sankara Vara Prasad, et al.
Publicado: (2016)

Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats
por: Prashanth, Anamthathmakula, et al.
Publicado: (2014)

Fatty acid desaturation index correlates with body mass and adiposity indices of obesity in Wistar NIN obese mutant rat strains WNIN/Ob and WNIN/GR-Ob
por: Jeyakumar, Shanmugam M, et al.
Publicado: (2009)

Carbenoxolone Treatment Ameliorated Metabolic Syndrome in WNIN/Ob Obese Rats, but Induced Severe Fat Loss and Glucose Intolerance in Lean Rats
por: Prasad Sakamuri, Siva Sankara Vara, et al.
Publicado: (2012)

ODP145 Epigenesis of 11beta-hydroxysteroid dehydrogenase 1 in the adipose tissue of aldosterone-producing adenoma
por: Aono, Daisuke, et al.
Publicado: (2022)

Characterisation of 11β-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat
por: Bujalska, Iwona J, et al.
Publicado: (2007)

Luteal 3beta-hydroxysteroid dehydrogenase and 20alpha-hydroxysteroid dehydrogenase activities in the rat corpus luteum of pseudopregnancy: Effect of the deciduoma reaction
por: Clementi, Marisa A, et al.
Publicado: (2004)

Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Tang, Lei, et al.
Publicado: (2015)

Effect of Eclipta prostrata on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Xu, Chenshu, et al.
Publicado: (2014)

Approach of Heterogeneous Spectrum Involving 3beta-Hydroxysteroid Dehydrogenase 2 Deficiency
por: Nicola, Andreea Gabriela, et al.
Publicado: (2022)

Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13
por: Liu, Shenping, et al.
Publicado: (2023)

Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity
por: Huebner, Hanna, et al.
Publicado: (2020)

11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia
por: Kosicka, Katarzyna, et al.
Publicado: (2016)

Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega
por: Doden, Heidi L., et al.
Publicado: (2021)

Cortisol Release From Adipose Tissue by 11β-Hydroxysteroid Dehydrogenase Type 1 in Humans
por: Stimson, Roland H., et al.
Publicado: (2009)

Mitochondrial 3 beta-hydroxysteroid dehydrogenase (HSD) is essential for the synthesis of progesterone by corpora lutea: An hypothesis
por: Chapman, John C, et al.
Publicado: (2005)

SUN-159 17-beta Hydroxysteroid Dehydrogenase 3 Deficiency in 1 Month Old Infant
por: Mathew, Deepa, et al.
Publicado: (2020)

Myriad Manifestations of 3-Beta-Hydroxysteroid Dehydrogenase 2 Deficiency—A Tale of Two Infants
por: Hathi, Deep, et al.
Publicado: (2022)

LBODP087 Unusual Presentation Of Salt-wasting 3-beta-hydroxysteroid Dehydrogenase-2 Deficiency
por: Vidal, Katherine, et al.
Publicado: (2022)

Vitamin A as a key regulator of obesity & its associated disorders: Evidences from an obese rat model
por: Jeyakumar, Shanmugam M., et al.
Publicado: (2015)

Pharmaconutrition strategy to resolve SARS-CoV-2-induced inflammatory cytokine storm in non-alcoholic fatty liver disease: Omega-3 long-chain polyunsaturated fatty acids
por: Jeyakumar, Shanmugam M, et al.
Publicado: (2021)

Stearoyl-CoA desaturase 1: A potential target for non-alcoholic fatty liver disease?-perspective on emerging experimental evidence
por: Jeyakumar, Shanmugam Murugaiha, et al.
Publicado: (2022)

Activation of sorbitol pathway in metabolic syndrome and increased susceptibility to cataract in Wistar-Obese rats
por: Reddy, Paduru Yadagiri, et al.
Publicado: (2012)

Luteinizing hormone induces expression of 11beta-hydroxysteroid dehydrogenase type 2 in rat Leydig cells
por: Wang, Qian, et al.
Publicado: (2009)

Placental 11-Beta Hydroxysteroid Dehydrogenase Methylation Is Associated with Newborn Growth and a Measure of Neurobehavioral Outcome
por: Marsit, Carmen J., et al.
Publicado: (2012)

SAT-023 Cyclic Regulation of 11 Beta-Hydroxysteroid Dehydrogenase Type 1 in Endometriosis in Rhesus Macaques
por: Slayden, Ov, et al.
Publicado: (2019)

Hydroxysteroid 17-Beta Dehydrogenase 6 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Hepatocellular Carcinoma
por: Wu, Min, et al.
Publicado: (2021)

11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome
por: Bailey, Matthew A.
Publicado: (2017)

Genomic data on breast cancer transcript profile modulation by 17beta-hydroxysteroid dehydrogenase type 1 and 17-beta-estradiol
por: Aka, Juliette A., et al.
Publicado: (2016)

The increased ratio of 11β-hydroxysteroid dehydrogenase type 1 versus 11β-hydroxysteroid dehydrogenase type 2 in chronic periodontitis irrespective of obesity
por: Nakata, Takaya, et al.
Publicado: (2016)

Species Used for Drug Testing Reveal Different Inhibition Susceptibility for 17beta-Hydroxysteroid Dehydrogenase Type 1
por: Möller, Gabriele, et al.
Publicado: (2010)

17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration
por: Aka, Juliette A, et al.
Publicado: (2012)

11Beta‐hydroxysteroid dehydrogenase‐1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis
por: Zou, Xiantong, et al.
Publicado: (2018)

Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain
por: Jeyakumar, Shanmugam M., et al.
Publicado: (2016)

Vitamin A Improves Hyperglycemia and Glucose-Intolerance through Regulation of Intracellular Signaling Pathways and Glycogen Synthesis in WNIN/GR-Ob Obese Rat Model
por: Jeyakumar, Shanmugam M., et al.
Publicado: (2017)

Carrot Juice Consumption Reduces High Fructose-Induced Adiposity in Rats and Body Weight and BMI in Type 2 Diabetic Subjects
por: Mahesh, Malleswarapu, et al.
Publicado: (2021)

Adrenal morphology and hydroxysteroid dehydrogenase enzymes in normal and intersex goats
por: Basrur, Parvathi K, et al.
Publicado: (1969)

Idiopathic intracranial hypertension, hormones, and 11β-hydroxysteroid dehydrogenases
por: Markey, Keira A, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_m88cf8e5k5rb0j1co23ctjpdkq