Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin

INTRODUCTION: Recent meta-analyses of genome-wide association studies revealed new genetic loci associated with fasting glycemia. For several of these loci, the mechanism of action in glucose homeostasis is unclear. The objective of the study was to establish metabolic phenotypes for these genetic v...

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Detalles Bibliográficos
Autores principales: Wagner, Robert, Dudziak, Katarzyna, Herzberg-Schäfer, Silke A., Machicao, Fausto, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161735/
https://www.ncbi.nlm.nih.gov/pubmed/21887289
http://dx.doi.org/10.1371/journal.pone.0023639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161735/
https://www.ncbi.nlm.nih.gov/pubmed/21887289
http://dx.doi.org/10.1371/journal.pone.0023639

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