Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559

BACKGROUND: TC-2559 is a selective α4β2 subtype of nicotinic acetylcholine receptor (nAChR) partial agonist and α4β2 nAChR activation has been related to antinociception. The aim of this study is to investigate the analgesic effect of TC-2559 and its underlying spinal mechanisms. RESULTS: 1) In vivo...

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Detalles Bibliográficos
Autores principales: Cheng, Long-Zhen, Han, Lei, Fan, Jing, Huang, Lan-Ting, Peng, Li-Chao, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161881/
https://www.ncbi.nlm.nih.gov/pubmed/21816108
http://dx.doi.org/10.1186/1744-8069-7-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161881/
https://www.ncbi.nlm.nih.gov/pubmed/21816108
http://dx.doi.org/10.1186/1744-8069-7-56

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