Cargando…

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

Exposure to influenza viruses is necessary, but not sufficient, for healthy human hosts to develop symptomatic illness. The host response is an important determinant of disease progression. In order to delineate host molecular responses that differentiate symptomatic and asymptomatic Influenza A inf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yongsheng, Zaas, Aimee K., Rao, Arvind, Dobigeon, Nicolas, Woolf, Peter J., Veldman, Timothy, Øien, N. Christine, McClain, Micah T., Varkey, Jay B., Nicholson, Bradley, Carin, Lawrence, Kingsmore, Stephen, Woods, Christopher W., Ginsburg, Geoffrey S., Hero, Alfred O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161909/ https://www.ncbi.nlm.nih.gov/pubmed/21901105 http://dx.doi.org/10.1371/journal.pgen.1002234

Ejemplares similares

A Host Transcriptional Signature for Presymptomatic Detection of Infection in Humans Exposed to Influenza H1N1 or H3N2
por: Woods, Christopher W., et al.
Publicado: (2013)

Unsupervised Bayesian linear unmixing of gene expression microarrays
por: Bazot, Cécile, et al.
Publicado: (2013)

A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses
por: McClain, Micah T., et al.
Publicado: (2016)

Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies
por: Chen, Bo, et al.
Publicado: (2010)

An individualized predictor of health and disease using paired reference and target samples
por: Liu, Tzu-Yu, et al.
Publicado: (2016)

Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset
por: Grzesiak, Emilia, et al.
Publicado: (2021)

2595. Murine Models for the Host Response to Typical and Atypical Pneumonia
por: Khan, Kirin, et al.
Publicado: (2019)

Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection
por: Burke, Thomas W., et al.
Publicado: (2017)

1721. A Transcriptional Signature of Acute Aspergillus Infection Offers High Diagnostic Accuracy Despite the Presence of Immunosuppression
por: Steinbrink, Julie M, et al.
Publicado: (2019)

1218. Comparing the Diagnostic Accuracy of Clinician Judgement to a Novel Host Response Diagnostic for Acute Respiratory Illness
por: Jaffe, Ian S, et al.
Publicado: (2020)

Systematic comparison of published host gene expression signatures for bacterial/viral discrimination
por: Bodkin, Nicholas, et al.
Publicado: (2022)

305. PBMC-Derived Transcriptomic Signatures Accurately Discriminate Between Viral, Bacterial, and Fungal Infections and can be Translated to Real-World Human Infections
por: Steinbrink, Julie M, et al.
Publicado: (2023)

A comparison of host response strategies to distinguish bacterial and viral infection
por: Ross, Melissa, et al.
Publicado: (2021)

1330. Evaluation of Multiple Host Response-Based Strategies to Classify Acute Respiratory Illness
por: Ross, Melissa H, et al.
Publicado: (2019)

Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii
por: Holcomb, Zachary E., et al.
Publicado: (2022)

A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study
por: McClain, Micah T, et al.
Publicado: (2021)

Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
por: Garrido, Carolina, et al.
Publicado: (2021)

1226. Performance of a Host Response Test for Bacterial/Viral Discrimination in Immunocompromised Patients
por: Mahle, Rachael E, et al.
Publicado: (2020)

Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
por: Ahn, Sun Hee, et al.
Publicado: (2013)

A host gene expression approach for identifying triggers of asthma exacerbations
por: Lydon, Emily C., et al.
Publicado: (2019)

Lid wiper epitheliopathy in symptomatic and asymptomatic dry eye subjects
por: Kamath, Vandana, et al.
Publicado: (2023)

Validation of a host response test to distinguish bacterial and viral respiratory infection
por: Lydon, Emily C., et al.
Publicado: (2019)

Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction
por: Rose, Jason J., et al.
Publicado: (2015)

The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches
por: Steinbrink, Julie M., et al.
Publicado: (2021)

SUN-LB35 Using Chromogranin A to Unmask the Great Masquerader: A Case Reportof a Minimally Symptomatic Pheochromocytoma
por: Goukassian, Ilona, et al.
Publicado: (2020)

A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies
por: Poore, Gregory D., et al.
Publicado: (2018)

Pre-exposure cognitive performance variability is associated with severity of respiratory infection
por: Zhai, Yaya, et al.
Publicado: (2022)

Dynamic Computational Model of Symptomatic Bacteremia to Inform Bacterial Separation Treatment Requirements
por: Miller, Sinead E., et al.
Publicado: (2016)

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches
por: McClain, Micah T., et al.
Publicado: (2020)

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population
por: Tillekeratne, L Gayani, et al.
Publicado: (2020)

An integrated transcriptome and expressed variant analysis of sepsis survival and death
por: Tsalik, Ephraim L, et al.
Publicado: (2014)

2014. TLDA Validation of a Host Response Signature to Discriminate Bacterial, Viral, and Non-infectious Causes of Illness
por: Lydon, Emily, et al.
Publicado: (2018)

2015. Host Gene Expression Identifies Infectious Triggers of Asthma Exacerbation
por: Lydon, Emily, et al.
Publicado: (2018)

Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
por: Sobel Leonard, Ashley, et al.
Publicado: (2016)

Asymptomatic and Symptomatic Carotid Stenosis: An Obsolete Classification?
por: Chatzikonstantinou, Anastasios, et al.
Publicado: (2012)

Human rhinovirus infections in symptomatic and asymptomatic subjects
por: Camargo, C.N., et al.
Publicado: (2012)

Asymptomatic and Pre-Symptomatic COVID-19 in China
por: Wu, Zunyou, et al.
Publicado: (2020)

Infectivity of asymptomatic versus symptomatic COVID-19
por: Sayampanathan, Andrew A, et al.
Publicado: (2021)

2012. FilmArray(®) Measurement of Host Response Signatures RapidLy Discriminates Viral, Bacterial, and Non-infectious Etiologies of Illness
por: Tsalik, Ephraim L, et al.
Publicado: (2018)

539. Prevalence of Symptomatic and Asymptomatic COVID-19 Infection in Pregnant Women and Their Infants in an Urban Hospital
por: Woods, Krystina L, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s9rbecq2njrf55k1n7r23f31g3