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Regulation of Caenorhabditis elegans p53/CEP-1–Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

Maintaining genome stability in the germline is thought to be an evolutionarily ancient role of the p53 family. The sole Caenorhabditis elegans p53 family member CEP-1 is required for apoptosis induction in meiotic, late-stage pachytene germ cells in response to DNA damage and meiotic recombination...

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Detalles Bibliográficos
Autores principales: Rutkowski, Rachael, Dickinson, Robin, Stewart, Graeme, Craig, Ashley, Schimpl, Marianne, Keyse, Stephen M., Gartner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161941/
https://www.ncbi.nlm.nih.gov/pubmed/21901106
http://dx.doi.org/10.1371/journal.pgen.1002238