Cargando…
Regulation of Caenorhabditis elegans p53/CEP-1–Dependent Germ Cell Apoptosis by Ras/MAPK Signaling
Maintaining genome stability in the germline is thought to be an evolutionarily ancient role of the p53 family. The sole Caenorhabditis elegans p53 family member CEP-1 is required for apoptosis induction in meiotic, late-stage pachytene germ cells in response to DNA damage and meiotic recombination...
Autores principales: | Rutkowski, Rachael, Dickinson, Robin, Stewart, Graeme, Craig, Ashley, Schimpl, Marianne, Keyse, Stephen M., Gartner, Anton |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161941/ https://www.ncbi.nlm.nih.gov/pubmed/21901106 http://dx.doi.org/10.1371/journal.pgen.1002238 |
Ejemplares similares
-
Nucleolar Proteins Suppress Caenorhabditis elegans Innate Immunity by Inhibiting p53/CEP-1
por: Fuhrman, Laura E., et al.
Publicado: (2009) -
Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans
por: Sterken, Mark G., et al.
Publicado: (2017) -
Harmine suppresses hyper-activated Ras–MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegans
por: Ji, Jiaojiao, et al.
Publicado: (2019) -
The hypoxia-response pathway modulates RAS/MAPK–mediated cell fate decisions in Caenorhabditis elegans
por: Maxeiner, Sabrina, et al.
Publicado: (2019) -
CEP-1, the Caenorhabditis elegans p53 Homolog, Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants
por: Baruah, Aiswarya, et al.
Publicado: (2014)