Non-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasion

BACKGROUND: The mucin MUC1, a type I transmembrane glycoprotein, is overexpressed in breast cancer and has been correlated with increased metastasis. We were the first to report binding between MUC1 and Intercellular adhesion molecule-1 (ICAM-1), which is expressed on stromal and endothelial cells t...

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Detalles Bibliográficos
Autores principales: Bernier, Ashlyn J, Zhang, Jing, Lillehoj, Erik, Shaw, Andrew RE, Gunasekara, Nirosha, Hugh, Judith C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161956/
https://www.ncbi.nlm.nih.gov/pubmed/21798038
http://dx.doi.org/10.1186/1476-4598-10-93

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