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Evidence for Hitchhiking of Deleterious Mutations within the Human Genome
Deleterious mutations present a significant obstacle to adaptive evolution. Deleterious mutations can inhibit the spread of linked adaptive mutations through a population; conversely, adaptive substitutions can increase the frequency of linked deleterious mutations and even result in their fixation....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161959/ https://www.ncbi.nlm.nih.gov/pubmed/21901107 http://dx.doi.org/10.1371/journal.pgen.1002240 |