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Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

This study evaluates the immunogenicity of the HIV envelope protein (env) in mice presented either attached to γ-retroviral virus-like-particles (VLPs), associated with cell-derived microsomes or as solubilized recombinant protein (gp160). The magnitude and polyfunctionality of the cellular immune r...

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Detalles Bibliográficos
Autores principales: Kirkegaard, Tea, Wheatley, Adam, Melchjorsen, Jesper, Bahrami, Shervin, Pedersen, Finn S, Center, Robert J, Purcell, Damian FJ, Ostergaard, Lars, Duch, Mogens, Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161963/
https://www.ncbi.nlm.nih.gov/pubmed/21806819
http://dx.doi.org/10.1186/1743-422X-8-381