Cargando…

Treponema denticola Major Outer Sheath Protein Induces Actin Assembly at Free Barbed Ends by a PIP2-Dependent Uncapping Mechanism in Fibroblasts

The major outer sheath protein (Msp) of Treponema denticola perturbs actin dynamics in fibroblasts by inducing actin reorganization, including subcortical actin filament assembly, leading to defective calcium flux, diminished integrin engagement of collagen, and retarded cell migration. Yet, its mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Visser, Michelle B., Koh, Adeline, Glogauer, Michael, Ellen, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161991/
https://www.ncbi.nlm.nih.gov/pubmed/21901132
http://dx.doi.org/10.1371/journal.pone.0023736