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Retinal Degeneration Progression Changes Lentiviral Vector Cell Targeting in the Retina
In normal mice, the lentiviral vector (LV) is very efficient to target the RPE cells, but transduces retinal neurons well only during development. In the present study, the tropism of LV has been investigated in the degenerating retina of mice, knowing that the retina structure changes during degene...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161995/ https://www.ncbi.nlm.nih.gov/pubmed/21901134 http://dx.doi.org/10.1371/journal.pone.0023782 |