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miR-143 Overexpression Impairs Growth of Human Colon Carcinoma Xenografts in Mice with Induction of Apoptosis and Inhibition of Proliferation

BACKGROUND: MicroRNAs (miRNAs) are aberrantly expressed in human cancer and involved in the (dys)regulation of cell survival, proliferation, differentiation and death. Specifically, miRNA-143 (miR-143) is down-regulated in human colon cancer. In the present study, we evaluated the role of miR-143 ov...

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Detalles Bibliográficos
Autores principales:	Borralho, Pedro M., Simões, André E. S., Gomes, Sofia E., Lima, Raquel T., Carvalho, Tânia, Ferreira, Duarte M. S., Vasconcelos, Maria H., Castro, Rui E., Rodrigues, Cecília M. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162002/ https://www.ncbi.nlm.nih.gov/pubmed/21901135 http://dx.doi.org/10.1371/journal.pone.0023787

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