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Computational Study of the Human Dystrophin Repeats: Interaction Properties and Molecular Dynamics
Dystrophin is a large protein involved in the rare genetic disease Duchenne muscular dystrophy (DMD). It functions as a mechanical linker between the cytoskeleton and the sarcolemma, and is able to resist shear stresses during muscle activity. In all, 75% of the dystrophin molecule consists of a lar...
Autores principales: | Legrand, Baptiste, Giudice, Emmanuel, Nicolas, Aurélie, Delalande, Olivier, Le Rumeur, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162007/ https://www.ncbi.nlm.nih.gov/pubmed/21901138 http://dx.doi.org/10.1371/journal.pone.0023819 |
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