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Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas
Microglia (brain resident macrophages) accumulate in malignant gliomas and instead of initiating the anti-tumor response, they switch to a pro-invasive phenotype, support tumor growth, invasion, angiogenesis and immunosuppression by release of cytokines/chemokines and extracellular matrix proteases....
Autores principales: | Gabrusiewicz, Konrad, Ellert-Miklaszewska, Aleksandra, Lipko, Maciej, Sielska, Malgorzata, Frankowska, Marta, Kaminska, Bozena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162015/ https://www.ncbi.nlm.nih.gov/pubmed/21901144 http://dx.doi.org/10.1371/journal.pone.0023902 |
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