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Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids
Glycine receptors (GlyRs) are transmitter-gated anion channels of the Cys-loop superfamily which mediate synaptic inhibition at spinal and selected supraspinal sites. Although they serve pivotal functions in motor control and sensory processing, they have yet to be exploited as drug targets partly b...
Autores principales: | Yévenes, Gonzalo E., Zeilhofer, Hanns Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162021/ https://www.ncbi.nlm.nih.gov/pubmed/21901142 http://dx.doi.org/10.1371/journal.pone.0023886 |
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