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Patterns of Gene Expression in Drosophila InsP(3) Receptor Mutant Larvae Reveal a Role for InsP(3) Signaling in Carbohydrate and Energy Metabolism

BACKGROUND: The Inositol 1,4,5-trisphosphate receptor (InsP(3)R) is an InsP(3) gated intracellular Ca(2+)-release channel. Characterization of Drosophila mutants for the InsP(3)R has demonstrated that InsP(3)-mediated Ca(2+) release is required in Drosophila larvae for growth and viability. METHODOL...

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Detalles Bibliográficos
Autores principales: Kumar, Satish, Dey, Debleena, Hasan, Gaiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162032/
https://www.ncbi.nlm.nih.gov/pubmed/21901161
http://dx.doi.org/10.1371/journal.pone.0024105