Chromosome Segregation: Monopolin Attracts Condensin

To segregate chromosomes properly, the cell must prevent merotely, an error that occurs when a single kinetochore is attached to microtubules emanating from both spindle poles. Recent evidence suggests that cooperation between Pcs1/Mde4 and condensin complexes plays an important role in preventing m...

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Detalles Bibliográficos
Autores principales: Dudas, Andrej, Polakova, Silvia, Gregan, Juraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162134/
https://www.ncbi.nlm.nih.gov/pubmed/21855006
http://dx.doi.org/10.1016/j.cub.2011.06.059
Descripción
Sumario:To segregate chromosomes properly, the cell must prevent merotely, an error that occurs when a single kinetochore is attached to microtubules emanating from both spindle poles. Recent evidence suggests that cooperation between Pcs1/Mde4 and condensin complexes plays an important role in preventing merotely.

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