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Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

The opportunistic fungal pathogen Aspergillus fumigatus adapts to iron limitation by upregulation of iron uptake mechanisms including siderophore biosynthesis and downregulation of iron-consuming pathways to spare iron. These metabolic changes depend mainly on the transcription factor HapX. Consiste...

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Detalles Bibliográficos
Autores principales:	Schrettl, Markus, Haas, Hubertus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Current Biology 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162135/ https://www.ncbi.nlm.nih.gov/pubmed/21724450 http://dx.doi.org/10.1016/j.mib.2011.06.002

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