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Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats
BACKGROUND: Serum IGF-I and IGF-II levels decline with age. IGF-I replacement therapy reduces the impact of age in rats. We have recently reported that IGF-II is able to act, in part, as an analogous of IGF-I in aging rats reducing oxidative damage in brain and liver associated with a normalization...
Autores principales: | Garcia-Fernandez, Maria, Sierra, Inma, Puche, Juan E, Guerra, Lucia, Castilla-Cortazar, Inma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162510/ https://www.ncbi.nlm.nih.gov/pubmed/21798010 http://dx.doi.org/10.1186/1479-5876-9-123 |
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