Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction

BACKGROUND: Chikungunya virus (CHIKV) is a mosquito transmitted alphavirus that recently caused several large scale outbreaks/epidemics of arthritic disease in tropics of Africa, Indian Ocean basin and South-East Asia. This re-emergence event was facilitated by genetic adaptation (E1-A226V substitut...

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Detalles Bibliográficos
Autores principales: Tsetsarkin, Konstantin A, McGee, Charles E, Higgs, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162544/
https://www.ncbi.nlm.nih.gov/pubmed/21801412
http://dx.doi.org/10.1186/1743-422X-8-376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162544/
https://www.ncbi.nlm.nih.gov/pubmed/21801412
http://dx.doi.org/10.1186/1743-422X-8-376

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