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1α,25-Dihydroxyvitamin D(3 )enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier
BACKGROUND: Cerebrovascular dysfunction has been considered to cause impairment of cerebral amyloid-β peptide (Aβ) clearance across the blood-brain barrier (BBB). Further, low levels of vitamin D are associated with increased risk of Alzheimer's disease, as well as vascular dysfunction. The pur...
Autores principales: | Ito, Shingo, Ohtsuki, Sumio, Nezu, Yasuko, Koitabashi, Yusuke, Murata, Sho, Terasaki, Tetsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162579/ https://www.ncbi.nlm.nih.gov/pubmed/21740543 http://dx.doi.org/10.1186/2045-8118-8-20 |
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