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Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent

BACKGROUND: Age is the major risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is an accumulation of amyloid-beta peptides (Aβ) in both the AD brain and the normal aging brain. Clearance of Aβ from the brain occurs via active transport at the blood-brain...

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Detalles Bibliográficos
Autores principales:	Pascale, Crissey L, Miller, Miles C, Chiu, Catherine, Boylan, Matthew, Caralopoulos, Ilias N, Gonzalez, Liliana, Johanson, Conrad E, Silverberg, Gerald D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162580/ https://www.ncbi.nlm.nih.gov/pubmed/21740544 http://dx.doi.org/10.1186/2045-8118-8-21

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