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The Effect of ACACB cis-Variants on Gene Expression and Metabolic Traits

BACKGROUND: Acetyl Coenzyme A carboxylase β (ACACB) is the rate-limiting enzyme in fatty acid oxidation, and continuous fatty acid oxidation in Acacb knock-out mice increases insulin sensitivity. Systematic human studies have not been performed to evaluate whether ACACB variants regulate gene expres...

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Detalles Bibliográficos
Autores principales:	Ma, Lijun, Mondal, Ashis K., Murea, Mariana, Sharma, Neeraj K., Tönjes, Anke, Langberg, Kurt A., Das, Swapan K., Franks, Paul W., Kovacs, Peter, Antinozzi, Peter A., Stumvoll, Michael, Parks, John S., Elbein, Steven C., Freedman, Barry I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162605/ https://www.ncbi.nlm.nih.gov/pubmed/21887335 http://dx.doi.org/10.1371/journal.pone.0023860

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