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Quantitative Analysis of Phase Wave of Gene Expression in the Mammalian Central Circadian Clock Network

BACKGROUND: The suprachiasmatic nucleus (SCN), the master circadian clock, is a heterogeneous oscillator network, yet displays a robust synchronization dynamics. Recent single-cell bioluminescent imaging revealed temporal gradients in circadian clock gene expression in the SCN ex vivo. However, due...

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Detalles Bibliográficos
Autores principales: Fukuda, Hirokazu, Tokuda, Isao, Hashimoto, Seiichi, Hayasaka, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162606/
https://www.ncbi.nlm.nih.gov/pubmed/21912598
http://dx.doi.org/10.1371/journal.pone.0023568