Cargando…

Efficient Differentiation of Embryonic Stem Cells into Hepatic Cells In Vitro Using a Feeder-Free Basement Membrane Substratum

The endoderm-inducing effect of the mesoderm-derived supportive cell line M15 on embryonic stem (ES) cells is partly mediated through the extracellular matrix, of which laminin α5 is a crucial component. Mouse ES or induced pluripotent stem cells cultured on a synthesized basement membrane (sBM) sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiraki, Nobuaki, Yamazoe, Taiji, Qin, Zeng, Ohgomori, Keiko, Mochitate, Katsumi, Kume, Kazuhiko, Kume, Shoen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162614/
https://www.ncbi.nlm.nih.gov/pubmed/21887386
http://dx.doi.org/10.1371/journal.pone.0024228