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Efficient Differentiation of Embryonic Stem Cells into Hepatic Cells In Vitro Using a Feeder-Free Basement Membrane Substratum
The endoderm-inducing effect of the mesoderm-derived supportive cell line M15 on embryonic stem (ES) cells is partly mediated through the extracellular matrix, of which laminin α5 is a crucial component. Mouse ES or induced pluripotent stem cells cultured on a synthesized basement membrane (sBM) sub...
Autores principales: | Shiraki, Nobuaki, Yamazoe, Taiji, Qin, Zeng, Ohgomori, Keiko, Mochitate, Katsumi, Kume, Kazuhiko, Kume, Shoen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162614/ https://www.ncbi.nlm.nih.gov/pubmed/21887386 http://dx.doi.org/10.1371/journal.pone.0024228 |
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