Thymidylate Synthase as a Prognostic Biomarker for Locally Advanced Rectal Cancer after multimodal Treatment

PURPOSE: For years, 5-fluorouracil (5-FU) has been the backbone of radiochemotherapy (RCT) of locally advanced rectal cancer. Its main target, thymidylate synthase (TS), is speculated to be an important biomarker for response prediction and long-term prognosis. In this study, we analyzed TS expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Conradi, Lena-Christin, Bleckmann, Annalen, Schirmer, Markus, Sprenger, Thilo, Jo, Peter, Homayounfar, Kia, Wolff, Hendrik A., Rothe, Hilka, Middel, Peter, Becker, Heinz, Ghadimi, Michael B., Beissbarth, Tim, Liersch, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Gastrointestinal Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162628/
https://www.ncbi.nlm.nih.gov/pubmed/21347782
http://dx.doi.org/10.1245/s10434-011-1608-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162628/
https://www.ncbi.nlm.nih.gov/pubmed/21347782
http://dx.doi.org/10.1245/s10434-011-1608-4

Ejemplares similares