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Thymidylate Synthase as a Prognostic Biomarker for Locally Advanced Rectal Cancer after multimodal Treatment

PURPOSE: For years, 5-fluorouracil (5-FU) has been the backbone of radiochemotherapy (RCT) of locally advanced rectal cancer. Its main target, thymidylate synthase (TS), is speculated to be an important biomarker for response prediction and long-term prognosis. In this study, we analyzed TS expressi...

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Detalles Bibliográficos
Autores principales:	Conradi, Lena-Christin, Bleckmann, Annalen, Schirmer, Markus, Sprenger, Thilo, Jo, Peter, Homayounfar, Kia, Wolff, Hendrik A., Rothe, Hilka, Middel, Peter, Becker, Heinz, Ghadimi, Michael B., Beissbarth, Tim, Liersch, Torsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Gastrointestinal Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162628/ https://www.ncbi.nlm.nih.gov/pubmed/21347782 http://dx.doi.org/10.1245/s10434-011-1608-4

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