Cargando…

Nanoparticle exposure at nanotechnology workplaces: A review

Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the corresponding nanomaterial taking into a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuhlbusch, Thomas AJ, Asbach, Christof, Fissan, Heinz, Göhler, Daniel, Stintz, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162892/
https://www.ncbi.nlm.nih.gov/pubmed/21794132
http://dx.doi.org/10.1186/1743-8977-8-22
_version_ 1782210893701971968
author Kuhlbusch, Thomas AJ
Asbach, Christof
Fissan, Heinz
Göhler, Daniel
Stintz, Michael
author_facet Kuhlbusch, Thomas AJ
Asbach, Christof
Fissan, Heinz
Göhler, Daniel
Stintz, Michael
author_sort Kuhlbusch, Thomas AJ
collection PubMed
description Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the corresponding nanomaterial taking into account also the environmental and product matrix. This review focuses on current available information from peer reviewed publications related to airborne nanomaterial exposure. Two approaches to derive realistic exposure values are differentiated and independently presented; those based on workplace measurements and the others based on simulations in laboratories. An assessment of the current available workplace measurement data using a matrix, which is related to nanomaterials and work processes, shows, that data are available on the likelihood of release and possible exposure. Laboratory studies are seen as an important complementary source of information on particle release processes and hence for possible exposure. In both cases, whether workplace measurements or laboratories studies, the issue of background particles is a major problem. From this review, major areas for future activities and focal points are identified.
format Online
Article
Text
id pubmed-3162892
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-31628922011-08-28 Nanoparticle exposure at nanotechnology workplaces: A review Kuhlbusch, Thomas AJ Asbach, Christof Fissan, Heinz Göhler, Daniel Stintz, Michael Part Fibre Toxicol Review Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the corresponding nanomaterial taking into account also the environmental and product matrix. This review focuses on current available information from peer reviewed publications related to airborne nanomaterial exposure. Two approaches to derive realistic exposure values are differentiated and independently presented; those based on workplace measurements and the others based on simulations in laboratories. An assessment of the current available workplace measurement data using a matrix, which is related to nanomaterials and work processes, shows, that data are available on the likelihood of release and possible exposure. Laboratory studies are seen as an important complementary source of information on particle release processes and hence for possible exposure. In both cases, whether workplace measurements or laboratories studies, the issue of background particles is a major problem. From this review, major areas for future activities and focal points are identified. BioMed Central 2011-07-27 /pmc/articles/PMC3162892/ /pubmed/21794132 http://dx.doi.org/10.1186/1743-8977-8-22 Text en Copyright ©2011 Kuhlbusch et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Kuhlbusch, Thomas AJ
Asbach, Christof
Fissan, Heinz
Göhler, Daniel
Stintz, Michael
Nanoparticle exposure at nanotechnology workplaces: A review
title Nanoparticle exposure at nanotechnology workplaces: A review
title_full Nanoparticle exposure at nanotechnology workplaces: A review
title_fullStr Nanoparticle exposure at nanotechnology workplaces: A review
title_full_unstemmed Nanoparticle exposure at nanotechnology workplaces: A review
title_short Nanoparticle exposure at nanotechnology workplaces: A review
title_sort nanoparticle exposure at nanotechnology workplaces: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162892/
https://www.ncbi.nlm.nih.gov/pubmed/21794132
http://dx.doi.org/10.1186/1743-8977-8-22
work_keys_str_mv AT kuhlbuschthomasaj nanoparticleexposureatnanotechnologyworkplacesareview
AT asbachchristof nanoparticleexposureatnanotechnologyworkplacesareview
AT fissanheinz nanoparticleexposureatnanotechnologyworkplacesareview
AT gohlerdaniel nanoparticleexposureatnanotechnologyworkplacesareview
AT stintzmichael nanoparticleexposureatnanotechnologyworkplacesareview