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Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes
BACKGROUND: Development of a standardized platform for the rapid expansion of tumor-infiltrating lymphocytes (TILs) with anti-tumor function from patients with limited TIL numbers or tumor tissues challenges their clinical application. METHODS: To facilitate adoptive immunotherapy, we applied geneti...
Autores principales: | Ye, Qunrui, Loisiou, Maria, Levine, Bruce L, Suhoski, Megan M, Riley, James L, June, Carl H, Coukos, George, Powell, Daniel J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162913/ https://www.ncbi.nlm.nih.gov/pubmed/21827675 http://dx.doi.org/10.1186/1479-5876-9-131 |
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