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Robust Association Tests Under Different Genetic Models, Allowing for Binary or Quantitative Traits and Covariates
The association of genetic variants with outcomes is usually assessed under an additive model, for example by the trend test. However, misspecification of the genetic model will lead to a reduction in power. More robust tests for association might therefore be preferred. A useful approach is to cons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162964/ https://www.ncbi.nlm.nih.gov/pubmed/21305351 http://dx.doi.org/10.1007/s10519-011-9450-9 |