Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients

Short-acting b2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. The aim of this study was to test whether genetic variants in PDE4D gene, a key regulator of b2-adrenoceptor-induced cAMP turnover in airway smooth muscle cells, affect the response to sh...

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Detalles Bibliográficos
Autores principales: Labuda, Malgorzata, Laberge, Sophie, Brière, Julie, Bérubé, Denis, Beaulieu, Patrick, Pastinen, Tomi, Krajinovic, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163044/
https://www.ncbi.nlm.nih.gov/pubmed/21876611
http://dx.doi.org/10.1155/2011/301695

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