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Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling

BACKGROUND: Human immunodeficiency virus (HIV) infected patients are at increased risk for the development of pulmonary arterial hypertension (PAH). Recent reports have demonstrated that HIV associated viral proteins induce reactive oxygen species (ROS) with resultant endothelial cell dysfunction an...

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Detalles Bibliográficos
Autores principales: Mermis, Joel, Gu, Haihua, Xue, Bing, Li, Fang, Tawfik, Ossama, Buch, Shilpa, Bartolome, Sonja, O'Brien-Ladner, Amy, Dhillon, Navneet K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163194/
https://www.ncbi.nlm.nih.gov/pubmed/21819559
http://dx.doi.org/10.1186/1465-9921-12-103