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An organotypic slice culture model of chronic white matter injury with maturation arrest of oligodendrocyte progenitors
BACKGROUND: CNS myelination disturbances commonly occur in chronic white matter lesions in neurodevelopmental and adult neurological disorders. Recent studies support that myelination failure can involve a disrupted cellular repair mechanism where oligodendrocyte (OL) progenitor cells (OPCs) prolife...
Autores principales: | Dean, Justin M, Riddle, Art, Maire, Jennifer, Hansen, Kelly D, Preston, Marnie, Barnes, Anthony P, Sherman, Larry S, Back, Stephen A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163199/ https://www.ncbi.nlm.nih.gov/pubmed/21729326 http://dx.doi.org/10.1186/1750-1326-6-46 |
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