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Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: An immunohistological study

BACKGROUND: Human β-defensins (hBD) are antimicrobial peptides that are an integral part of bone innate immunity. Recently, it could be shown that expression of hBD-1, -2 and -3 were upregulated in cases of osteomyelitis of the jaws. In order to gain insight into the possible impairment of hBD metab...

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Detalles Bibliográficos
Autores principales: Stockmann, Philipp, Wehrhan, Falk, Schwarz-Furlan, Stephan, Stelzle, Florian, Trabert, Susanne, Neukam, Friedrich W, Nkenke, Emeka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163206/
https://www.ncbi.nlm.nih.gov/pubmed/21843332
http://dx.doi.org/10.1186/1479-5876-9-135