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Enhanced Antihypertensive Activity of Candesartan Cilexetil Nanosuspension: Formulation, Characterization and Pharmacodynamic Study

The objective of the present investigation was to enhance the oral bioavailability of practically insoluble Candesartan cilexetil [CC] by preparing nanosuspension. The nanosuspension was prepared by media milling using zirconium oxide beads and converted to solid state by spray drying. The spray dri...

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Detalles Bibliográficos
Autores principales: Detroja, Chetan, Chavhan, Sandip, Sawant, Krutika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163369/
https://www.ncbi.nlm.nih.gov/pubmed/21886909
http://dx.doi.org/10.3797/scipharm.1103-17