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A retrosynthetic biology approach to metabolic pathway design for therapeutic production
BACKGROUND: Synthetic biology is used to develop cell factories for production of chemicals by constructively importing heterologous pathways into industrial microorganisms. In this work we present a retrosynthetic approach to the production of therapeutics with the goal of developing an in situ dru...
Autores principales: | Carbonell, Pablo, Planson, Anne-Gaëlle, Fichera, Davide, Faulon, Jean-Loup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163555/ https://www.ncbi.nlm.nih.gov/pubmed/21819595 http://dx.doi.org/10.1186/1752-0509-5-122 |
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