Relevance of Stereotyped B-Cell Receptors in the Context of the Molecular, Cytogenetic and Clinical Features of Chronic Lymphocytic Leukemia

Highly homologous B-cell receptors, characterized by non-random combinations of immunoglobulin heavy-chain variable (IGHV) genes and heavy-chain complementarity determining region-3 (HCDR3), are expressed in a recurrent fraction of patients affected by chronic lymphocytic leukemia (CLL). We investig...

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Detalles Bibliográficos
Autores principales: Maura, Francesco, Cutrona, Giovanna, Fabris, Sonia, Colombo, Monica, Tuana, Giacomo, Agnelli, Luca, Matis, Serena, Lionetti, Marta, Gentile, Massimo, Recchia, Anna Grazia, Di Raimondo, Francesco, Musolino, Caterina, Ilariucci, Fiorella, Di Renzo, Nicola, Pesce, Emanuela, Molica, Stefano, Federico, Massimo, Cortelezzi, Agostino, Morabito, Fortunato, Ferrarini, Manlio, Neri, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163661/
https://www.ncbi.nlm.nih.gov/pubmed/21897877
http://dx.doi.org/10.1371/journal.pone.0024313

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