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Betacellulin-Induced Beta Cell Proliferation and Regeneration Is Mediated by Activation of ErbB-1 and ErbB-2 Receptors

BACKGROUND: Betacellulin (BTC), a member of the epidermal growth factor family, is known to play an important role in regulating growth and differentiation of pancreatic beta cells. Growth-promoting actions of BTC are mediated by epidermal growth factor receptors (ErbBs), namely ErbB-1, ErbB-2, ErbB...

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Detalles Bibliográficos
Autores principales: Oh, Yoon Sin, Shin, Seungjin, Lee, Youn-Jung, Kim, Eung Hwi, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163663/
https://www.ncbi.nlm.nih.gov/pubmed/21897861
http://dx.doi.org/10.1371/journal.pone.0023894

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