Cargando…

Interferon-β Signaling Contributes to Ras Transformation

Increasing evidence has pointed to activated type I interferon signaling in tumors. However, the molecular basis for such activation and its role in tumorigenesis remain unclear. In the current studies, we report that activation of type I interferon (IFN) signaling in tumor cells is primarily due to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Yu-Chen, Pestka, Sidney, Wang, Lu-Hai, Runnels, Loren W., Wan, Shan, Lyu, Yi Lisa, Liu, Leroy F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163666/ https://www.ncbi.nlm.nih.gov/pubmed/21897875 http://dx.doi.org/10.1371/journal.pone.0024291

Ejemplares similares

Chemotherapeutics and Radiation Stimulate MHC Class I Expression through Elevated Interferon-beta Signaling in Breast Cancer Cells
por: Wan, Shan, et al.
Publicado: (2012)

The Role of Wild-Type RAS in Oncogenic RAS Transformation
por: Sheffels, Erin, et al.
Publicado: (2021)

Identification of a Novel Binding Partner of Phospholipase Cβ1: Translin-Associated Factor X
por: Aisiku, Omozuanvbo R., et al.
Publicado: (2010)

Compartmentalized Ras signaling differentially contributes to phenotypic outputs()
por: Aran, Veronica, et al.
Publicado: (2013)

RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma
por: Yang, Dazhi, et al.
Publicado: (2011)

Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling
por: Shin, Wookjin, et al.
Publicado: (2018)

Transforming ras oncogenes and multistage carcinogenesis.
por: Balmain, A.
Publicado: (1985)

Dynamic regulation of RAS and RAS signaling
por: Kolch, Walter, et al.
Publicado: (2023)

ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant
por: Tago, Kenji, et al.
Publicado: (2017)

The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction
por: Soriano, Olga, et al.
Publicado: (2021)

Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways
por: Janda, Elzbieta, et al.
Publicado: (2002)

Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V
por: Schmees, C., et al.
Publicado: (2012)

Impact of Zinc Transport Mechanisms on Embryonic and Brain Development
por: Willekens, Jeremy, et al.
Publicado: (2022)

Enhanced Interferon-β Response Contributes to Eosinophilic Chronic Rhinosinusitis
por: Jang, Yong Ju, et al.
Publicado: (2018)

Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition
por: Hanker, Ariella B, et al.
Publicado: (2009)

H-Ras Exerts Opposing Effects on Type I Interferon Responses Depending on Its Activation Status
por: Chen, Guann-An, et al.
Publicado: (2017)

RAS variant signalling
por: Mo, Stephanie P., et al.
Publicado: (2018)

Ca(2+) Signaling in Cardiac Fibroblasts and Fibrosis-Associated Heart Diseases
por: Feng, Jianlin, et al.
Publicado: (2019)

The role of non-ras transforming genes in chemical carcinogenesis.
por: Cooper, C S
Publicado: (1991)

Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again
por: Abankwa, Daniel, et al.
Publicado: (2020)

Essential Role of Cdc42 in Ras-Induced Transformation Revealed by Gene Targeting
por: Stengel, Kristy R., et al.
Publicado: (2012)

Tumour‐derived transforming growth factor‐β signalling contributes to fibrosis in patients with cancer cachexia
por: Lima, Joanna D.C.C., et al.
Publicado: (2019)

Interferon Signaling-Dependent Contribution of Glycolysis to Rubella Virus Infection
por: Schilling, Erik, et al.
Publicado: (2022)

Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells
por: Arase, Mayu, et al.
Publicado: (2017)

Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells
por: Lin, Shu, et al.
Publicado: (2012)

Graded inhibition of oncogenic Ras-signaling by multivalent Ras-binding domains
por: Augsten, Martin, et al.
Publicado: (2014)

Regulation of the RAS signaling network
por: Maruta, Hiroshi, et al.
Publicado: (1996)

Compartmentalized Ras signaling in lymphocytes
por: Philips, MR
Publicado: (2009)

Ras signalling in pathogenic yeasts
por: Pentland, Daniel R., et al.
Publicado: (2017)

Regulation of Ras Signaling by S-Nitrosylation
por: Simão, Sónia, et al.
Publicado: (2023)

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia
Publicado: (1995)

Osteopontin is required for full expression of the transformed phenotype by the ras oncogene
por: Wu, Y, et al.
Publicado: (2000)

Localization of phospholipase A2 in normal and ras-transformed cells
Publicado: (1988)

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
por: Lock, Rebecca, et al.
Publicado: (2011)

Requirement for c-ras proteins during viral oncogene transformation
por: Smith, Mark R., et al.
Publicado: (1986)

Targeting K-Ras and apoptosis-driven cellular transformation in cancer
por: Godwin, Isha, et al.
Publicado: (2021)

The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation
por: Gough, Daniel J., et al.
Publicado: (2013)

Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation
por: Chen, Sisi, et al.
Publicado: (2022)

Selective killing of K-ras–transformed pancreatic cancer cells by targeting NAD(P)H oxidase
por: Wang, Peng, et al.
Publicado: (2015)

Membrane Thickness as a Key Factor Contributing to the Activation of Osmosensors and Essential Ras Signaling Pathways
por: Cohen, B. Eleazar
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dskusc8faaoo0hskfs55m0lprd