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Expression of APOBEC3G/3F and G-to-A Hypermutation Levels in HIV-1-Infected Children with Different Profiles of Disease Progression

OBJECTIVE: Increasing evidence has accumulated showing the role of APOBEC3G (A3G) and 3F (A3F) in the control of HIV-1 replication and disease progression in humans. However, very few studies have been conducted in HIV-infected children. Here, we analyzed the levels of A3G and A3F expression and ind...

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Detalles Bibliográficos
Autores principales: Amoêdo, Nívea D., Afonso, Adriana O., Cunha, Sílvia M., Oliveira, Ricardo H., Machado, Elizabeth S., Soares, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163681/
https://www.ncbi.nlm.nih.gov/pubmed/21897871
http://dx.doi.org/10.1371/journal.pone.0024118