MicroRNAs can generate thresholds in target gene expression

MicroRNAs (miRNAs) are short, highly conserved non-coding RNA molecules that repress gene expression in a sequence-dependent manner. We performed single-cell measurements using quantitative fluorescence microscopy and flow cytometry to monitor a target gene’s protein expression in the presence and a...

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Detalles Bibliográficos
Autores principales: Mukherji, Shankar, Ebert, Margaret S., Zheng, Grace X., Tsang, John S., Sharp, Phillip A., van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163764/
https://www.ncbi.nlm.nih.gov/pubmed/21857679
http://dx.doi.org/10.1038/ng.905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163764/
https://www.ncbi.nlm.nih.gov/pubmed/21857679
http://dx.doi.org/10.1038/ng.905

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