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Linkage Specificity and Role of Properdin in Activation of the Alternative Complement Pathway by Fungal Glycans
Fungal cell walls are predominantly composed of glucans, mannans, and chitin. Recognition of these glycans by the innate immune system is a critical component of host defenses against the mycoses. Complement, an important arm of innate immunity, plays a significant role in fungal pathogenesis, espec...
Autores principales: | Agarwal, Sarika, Specht, Charles A., Huang, Haibin, Ostroff, Gary R., Ram, Sanjay, Rice, Peter A., Levitz, Stuart M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163941/ https://www.ncbi.nlm.nih.gov/pubmed/21878570 http://dx.doi.org/10.1128/mBio.00178-11 |
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