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Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia
Growth factor Neuregulin 1 (NRG1) plays an essential role in development and organization of the cerebral cortex. NRG1 and its receptors, ERBB3 and ERBB4, have been implicated in genetic susceptibility for schizophrenia. Disease symptoms include asociality and altered social interaction. To investig...
Autores principales: | Moy, Sheryl S., Troy Ghashghaei, H., Nonneman, Randal J., Weimer, Jill M., Yokota, Yukako, Lee, Daekee, Lai, Cary, Threadgill, David W., Anton, E. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164004/ https://www.ncbi.nlm.nih.gov/pubmed/21547722 http://dx.doi.org/10.1007/s11689-009-9017-8 |
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