Utility of Survival Motor Neuron ELISA for Spinal Muscular Atrophy Clinical and Preclinical Analyses

OBJECTIVES: Genetic defects leading to the reduction of the survival motor neuron protein (SMN) are a causal factor for Spinal Muscular Atrophy (SMA). While there are a number of therapies under evaluation as potential treatments for SMA, there is a critical lack of a biomarker method for assessing...

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Detalles Bibliográficos
Autores principales: Kobayashi, Dione T., Olson, Rory J., Sly, Laurel, Swanson, Chad J., Chung, Brett, Naryshkin, Nikolai, Narasimhan, Jana, Bhattacharyya, Anuradha, Mullenix, Michael, Chen, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164180/
https://www.ncbi.nlm.nih.gov/pubmed/21904622
http://dx.doi.org/10.1371/journal.pone.0024269

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